Polygonum Cuspidatum Extract - Resveratrol

Model NO.: Resveratrol 50%,98%HPLC

Quantity:

Product Description

Technical Data Sheet

*Product Name*	Polygonum Cuspidatum Extract
*Latin Name*	Reynoutria japonica Houtt.
*Part of Plant*	Root
*Active Ingredient*	Resveratrol50%,98%HPLC
*CAS NO.*	501-36-0
*Chemical Formula*	C20H22O8
*Solubility*	Insoluble in water, easily soluble in ether, methanol, acetone, ethyl acetate and other organic solvents
*Stability*	Resveratrol fluoresces under UV light exposure at 366 nm. Jeandet et al. determined the UV spectral properties of resveratrol and its infrared absorption peaks at 2800 to 3500 cm (OH bond) and 965 cm (double bond trans). Experiments have shown that trans-resveratrol is stable even after a few months of complete isolation of light, except in high pH buffers.
*Description*	Polygonum cuspidatum, commonly known as Asian knotweed or Japanese knotweed, is a large, herbaceous perennial plant of the knotweed and buckwheat family Polygonaceae.Resveratrol and emodin are the main functional components in Polygonum cuspidatum,exhibits a wide range of antioxidant properties, Resveratrol has also been shown to help cardiovascular health and blood circulation, relieve pain, clear away heat, remove dampness, remove poison and remove phlegm. Other ingredients including tananthrone, emodin methyl ether and rhein all have anti-inflammatory, anti-arthritis and anti-microbial activities.
*Package*	25kg fiber drum with sealed inner polyethylene liner
*Shelf-life*	24 months, if tightly sealed in a cool and dry place
*Certificates*	ISO22000, HACCP, KOSHER, HALAL, Organic Certificates

Bio-pharmaceuticals

⭐Anti-aging
Studies have found that resveratrol activates acetylase and increases the lifespan of yeasts, sparking a boom in research on the anti-aging of resveratrol. Howitz et al. found that resveratrol can be used as an activator of the strongest silent information regulation 2 homolog1 (SIRT1), mimicking calorie restriction (CR) anti-aging responses, and participating in the regulation of the mean life cycle of organic organisms. CR is a strong inducer of SIRT1, which can increase the expression of SIRT1 in organ tissues such as brain, heart, intestine, kidney, muscle and fat, cr can cause physiological changes that delay aging and prolong life, the most significant can be extended by 50%. Studies have confirmed the effects of resveratrol in prolonging the lifespan of yeast, nematodes, fruit flies and low-grade fish.
⭐Anti-tumor, anti-cancer
Resveratrol has a significant inhibitory effect on a variety of tumor cells such as murine hepatocellular carcinoma, breast cancer, colon cancer, stomach cancer, and leukemia. Some scholars have confirmed by MTT method and flow cytometry that resveratrol has a significant inhibitory effect on melanoma cells.
It has been reported that resveratrol can enhance cancer radiation therapy, exert the effect of"1+1>2", and effectively inhibit the role of cancer stem cells. But so far, due to the complexity of resveratrol's anti-tumor mechanism, researchers have not reached a consensus on its mechanism of action.
⭐Prevention and treatment of cardiovascular disease
Epidemiological studies have found that the phenomenon of"Frenchparadox", that is, the Daily intake of large amounts of fat in French people, but the incidence and mortality of cardiovascular disease are significantly lower than in other European countries, may be related to their daily large consumption of wine, and resveratrol may be its main active protective factor. Studies have shown that resveratrol can regulate the level of cholesterol in the blood through binding to estrogen receptors in the human body, inhibit platelet formation and blood clots adhering to the blood vessel wall, thereby inhibiting and alleviating the occurrence and development of cardiovascular disease and reducing the risk of cardiovascular disease in the human body.

*Item*	*Standard*	*Test Method*
Assay	Resveratrol ≥98%	HPLC
Appearance	WhitePowder	Visual
Odor	Characteristic	Organoleptic
Particle Size	≥95% pass 80 mesh	Ch. P. C. Rule 47
Loss on Drying	≤5.00%	Ch. P. C. Rule 52
Ash	≤5.00%	Ch. P. C. Rule 2302
Heavy Metals	≤10mg/kg	Colorimetric method
Arsenic (As)	≤3mg/kg	Ch. P. C. Rule 21-ICP-MS
Lead (Pb)	≤2mg/kg	Ch. P. C. Rule 21-ICP-MS
Mercury (Hg)	≤2mg/kg	Ch. P. C. Rule 21-ICP-MS
Cadmium (Cd)	≤2mg/kg	Ch. P. C. Rule 21-ICP-MS
Ethanol	≤500mg/kg	GC-MS
Total Plate Count	≤5000CFU/g	ISO 4833-1:2013
Total Yeast & Mold	≤500CFU/g	ISO 21527:2008
Coliforms	≤10CFU/g	ISO 21527:2008
Salmonella	Negative	ISO 6579-1:2017

*Supplier's* *Name*	Hunan Delore Natural Products Co., Ltd
*Supplier'sEmail***	info@delore.cn
*Supplier'sWebsite***	www.delore.cn /www.deloresolutions.com
*Supplier's Address*	Bld#7B, Depu Parkview Green, Changsha, Hunan, 410100, China