Hunan Delore Natural Products Co., LtdAbout UsDePu Parkview Green, No.1,Luo Sitang Road, Changsha national economic&technical development zone,HunanHunan Delore Natural Products Co., Ltd is located in Changsha city, Hunan Province, China.
Delore is a manufacturer of plant extracts and its advantages are as below:
1. Cultivation: Delore has self-owned planting bases to ensure the quality of raw materials from the source
2. Production: Delore is equipped the most advanced equipments to meet the HACCP/ISO standards
3. Quality control: Delore has a third-party lab to ensure the quality of each batch before delivery
4. R&D support: Delore has a professional team that offers technical supports to serve clients better
5. Sales service: De
Synephrine is a kind of alkaloid found in citrus family, such as bitter orange,seville orange, sour orange or Zhi Shi in Chinese.
Solubility
Soluble in water, insoluble in ethanol, almost insoluble in chloroform and ether. Reference data: Water Solubility is 18.6 mg/mL.
Safety
Studies in humans indicate that the synephrine has a wide margin of safety with an oral LD50 greater than 2500 mg/kg in rats. Approximately 30 human studies involving over 600 subjects have demonstrated that synephrine does not produce cardiovascular effects at doses up to 100 mg.
Package
25kg fiber drum with sealed inner polyethylene liner
Shelf-life
24 months, if tightly sealed in a cool and dry place
Synephrine as a weight loss promoter, its mechanism is to stimulate β- lipid decomposition and subsequent thermogenesis due to adrenoceptor. Most dietary supplements containing synephrine also contain other different ingredients, mainly caffeine, salicylic acid and ephedrine. The combination of the above chemical components can improve the weight loss effect of synephrine.
Pharmaceuticals
Synephrine can constrict blood vessels, produce high blood pressure and dilate trachea and bronchus. The results of intravenous injection test in anesthetized cats showed that synephrine could resist bronchoconstriction. Clinically, synephrine is also used to treat hypotension, collapse, body weight and postural hypotension during bronchial asthma surgery and anesthesia. In addition, synephrine has a certain excitatory effect on cardiac receptors, which can increase blood pressure and improve mental activities. Therefore, it can be used as a mild stimulant.
Food & Beverage
It can be used as food additive in candy, cake, biscuit, sugar cube, nutrition, tea bag, etc. it can also be used in beverages, such as tea, coffee, sports drinks and chewing gum
Item
Standard
Test Method
Assay
Synephrine≥Agreed Value
HPLC
Appearance
White powder
Visual
Odor
Characteristic
Organoleptic
Particle Size
≥95% pass 80 mesh
Ch. P. C. Rule 47
Loss on Drying
≤5.00%
Ch. P. C. Rule 52
Ash
≤5.00%
Ch. P. C. Rule 2302
Heavy Metals
≤10mg/kg
Colorimetric method
Arsenic (As)
≤3mg/kg
Ch. P. C. Rule 21-ICP-MS
Lead (Pb)
≤2mg/kg
Ch. P. C. Rule 21-ICP-MS
Mercury (Hg)
≤2mg/kg
Ch. P. C. Rule 21-ICP-MS
Cadmium (Cd)
≤2mg/kg
Ch. P. C. Rule 21-ICP-MS
Ethanol
≤500mg/kg
GC-MS
Total Plate Count
≤5000CFU/g
ISO 4833-1:2013
Total Yeast & Mold
≤500CFU/g
ISO 21527:2008
Coliforms
≤10CFU/g
ISO 21527:2008
Salmonella
Negative
ISO 6579-1:2017
Supplier's Name
Hunan Delore Natural Products Co., Ltd
Supplier'sEmail
info@delore.cn
Supplier'sWebsite
www.delore.cn /www.deloresolutions.com
Supplier's Address
Bld#7B, Depu Parkview Green, Changsha, Hunan, 410100, China