Technical Data Sheet
| Product Name | MulberryExtract |
| Latin Name | Mulberry alba L. |
| Part of Plant | Leaf |
| Active Ingredient | 1-DNJ 1%~30% |
| CAS NO. | 19130-96-2 |
| Chemical Formula | C6H13NO4 |
| Solubility | It is easily soluble in water and ethanol |
| Description | Mulberry leaf extract was obtained from mulberry leaf powder processed from the first to third new leaves of mulberry branches in the late period of spring silkworm or before frost's fall. The powder was dried in the shade, crushed, then extracted with n-butanol, 90% ethanol and water, respectively, and then sprayed and dried. The extract contains a variety of physiological active substances such as mulberry leaf flavonoids, mulberry leaf polyphenols, mulberry leaf polysaccharides, DNJ, and GABA, which are used to prevent and treat cardiovascular and cerebrovascular diseases, hyperlipidemia, diabetes, obesity and anti-aging. |
| Package | 25kg fiber drum with sealed inner polyethylene liner |
| Shelf-life | 24 months, if tightly sealed in a cool and dry place |
| Certificates | ISO22000, HACCP, KOSHER, HALAL, Organic Certificates |
| Bio-pharmaceuticals | ⭐Triple pathways co-lower diabetes As a potent inhibitor of glucose metabolism enzymes (such as α-glucosidase, hexokinase, glucuronidase and glycogen phosphatase, etc.), DNJ can significantly delay the degradation process of polysaccharides, reduce the peak of postprandial blood glucose, and stabilize fasting blood glucose. In addition, DNJ has an insulin sensitizing effect, improving insulin resistance. ⭐Lowers postprandial blood sugar. α-glucosidase is mainly distributed in the human small intestine and plays an important role in the decomposition of carbohydrates. They are responsible for breaking down oligosaccharides such as oligosaccharides in food into simple sugars, such as glucose. This glucose enters the body through the intestinal wall, causing a sharp increase in the body's blood glucose concentration. DNJ is a naturally potent α-glucosidase inhibitor that can competitively bind α-glucosidase in the small intestine, and the affinity is stronger than that of oligosaccharides such as sucrose and maltose and α-glucosidase, reducing the probability of oligosaccharide binding to α-glucosidase, thereby inhibiting fructose decomposition into glucose, and a large amount of sugar will not be absorbed and sent into the large intestine. Due to the action of DNJ, less glucose enters the bloodstream, so blood sugar is worth maintaining at healthy levels. ⭐Stabilizes fasting blood sugar. DNJ has the inhibitory activity of glycogen phosphorylase, which can slow down the degradation of liver glycogen into glucose, thereby smoothing fasting blood glucose. The"excess"glucose in the human body is stored in the liver in the form of glycogen. Glycogen can be broken down into glucose under the action of glycogen phosphorylase and released into the bloodstream, supplying muscles and other organ activities. Glycogen is one of the main sources of energy for providing physical activity. With the mutual conversion between glycogen and glucose, the blood sugar of normal people is in dynamic balance. In diabetic patients, due to the dysfunction of glucose metabolism, too much glycogen will be broken down into glucose, resulting in an abnormal increase in fasting blood glucose values. DNJ can achieve the effect of stabilizing fasting blood glucose by inhibiting the activity of glycogen phosphorylase and preventing the excessive glycogen decomposition into glucose caused by the increase in blood glucose. ⭐Improves insulin resistance. DNJ can improve symptoms of insulin resistance by correcting lipid metabolism, slowing glucose production, and sensitizing insulin. Insulin resistance refers to various reasons (mainly genetic factors and obesity), so that insulin promotes glucose uptake and utilization efficiency declines, the body compensates for the secretion of too much insulin. Insulin resistance produces hyperinsulinemia to maintain the stability of blood sugar in the body. If the human body is in a state of insulin resistance for a long time, it will greatly increase the burden on the pancreas, which may lead to the failure of the pancreas's insulin secretion function, and may develop diabetes. DNJ can improve symptoms of insulin resistance by maintaining healthy blood sugar, correcting lipid metabolism, and increasing insulin sensitivity. |
| Item | Standard | Test Method |
| Assay | 1-DNJ ≥1% | HPLC |
| Appearance | Light Brown Yellow Powder | Visual |
| Odor | Characteristic | Organoleptic |
| Particle Size | ≥95% pass 80 mesh | Ch. P. C. Rule 47 |
| Loss on Drying | ≤5.00% | Ch. P. C. Rule 52 |
| Ash | ≤5.00% | Ch. P. C. Rule 2302 |
| Heavy Metals | ≤10mg/kg | Colorimetric method |
| Arsenic (As) | ≤3mg/kg | Ch. P. C. Rule 21-ICP-MS |
| Lead (Pb) | ≤2mg/kg | Ch. P. C. Rule 21-ICP-MS |
| Mercury (Hg) | ≤2mg/kg | Ch. P. C. Rule 21-ICP-MS |
| Cadmium (Cd) | ≤2mg/kg | Ch. P. C. Rule 21-ICP-MS |
| Ethanol | ≤500mg/kg | GC-MS |
| Total Plate Count | ≤5000CFU/g | ISO 4833-1:2013 |
| Total Yeast & Mold | ≤500CFU/g | ISO 21527:2008 |
| Coliforms | ≤10CFU/g | ISO 21527:2008 |
| Salmonella | Negative | ISO 6579-1:2017 |
| Supplier's Name | Hunan Delore Natural Products Co., Ltd  |
| Supplier'sEmail | info@delore.cn |
| Supplier'sWebsite | www.delore.cn /www.deloresolutions.com |
| Supplier's Address | Bld#7B, Depu Parkview Green, Changsha, Hunan, 410100, China |
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