Epimedium Extract - Icariin

Model NO.: Icariin 10%~98%

Quantity:

Product Description

Technical Data Sheet

*Product Name*	Epimedium Extract
*Latin Name*	Epimedium grandiflorum L.
*Part of Plant*	Leaf
*Active Ingredient*	Icariin 10%~98%
*CAS NO.*	489-32-7
*Chemical Formula*	C33H40O15
*Solubility*	Soluble in water, soluble in ethanol, ethyl acetate, insoluble in ether, benzene, chloroform.
*Stability*	The reaction with ferric chloride is green, and the reaction with magnesium hydrochloride powder is orange-red.
*Description*	Epimedium grandiflorum L is a Chinese herbal medicine with proven efficacy in treating cardiovascular diseases and osteoporosis, and in improving sexual and neurological functions. Its root and leaf have the same efficacy, but the medicinal efficacy of the leaves is stronger than that of the roots, because the content of medicinal ingredients in the leaves is higher. The leaves are mostly used for the treatment of impotence and premature ejaculation,and the root is mostly used for the treatment of rheumatic bone pain.
*Package*	25kg fiber drum with sealed inner polyethylene liner
*Shelf-life*	24 months, if tightly sealed in a cool and dry place
*Certificates*	ISO22000, HACCP, KOSHER, HALAL, Organic Certificates

Bio-pharmaceuticals

⭐Enhanced sexual function
It can enhance the secretion function of the hypothalamic-pituitary gland, the adrenal cortex axis, the thymus axis and other endocrine systems. Epimedium boiling solution 1ml 100g body weight for female rats, after 5 days can improve the pituitary gland's response to the production of hormones produced by the luteinous body and the responsiveness of ovarian luteinizing hormone; Significantly increased anterior pituitary, ovarian, and uterine weight in normal rats. Epimedium has an erotic effect, this effect is due to excessive semen secretion, seminal vesicles filled, stimulate the sensory nerves and indirectly excite sexual desire. Epimedium flow extract has the effect of promoting the secretion of canine semen, and its leaves and roots have the strongest effect, followed by the fruit and the weakest stem; Weight-increasing methods of prostate, seminal vesicles, and levator ani muscles (mice) demonstrated that Epimedium extract has a male hormone-like effect, and its potency is comparable to that of 7.5 u g of testosterone. Epimedium products also have the effect of significantly improving sexual function and increasing plasma testosterone content, and their intensity of action is not significantly different from intramuscular testosterone, and significantly promote testicular tissue hyperplasia and secretion.
⭐Enhances the body's immune function: Giving mice a daily gastric icariin 20mg/kg can significantly increase the weight of their spleens, and can promote the proliferation of antigen-activated lymphocytes, significantly improve the level of spleen antibody production, and significantly increase the number of hemolytic plaque formations in the spleen of mice.
⭐Anti-aging
It significantly restored the function of T and B lymphocyte proliferation reactions in male mice with D-galactose senescence model, and significantly improved the activity of total SOD in the liver of mice, reduced the formation of lipid peroxide in liver tissues, and reduced the formation of lipofuscin in heart, liver and other tissues, but did not significantly reduce the lipofuscin of the brain. Epimedium's compound preparation"Two Immortal Capsules"suspension can prolong the silkworm larval stage, pupa stage, adult stage and total lifespan; The daily administration of 1.25g/kg can reduce the content of lipofuscin in the brain, heart and liver of mice, increase the level of IgG and total complement in the blood, and enhance the phagocytic function of neutrophils and peritoneal macrophages.
⭐Beneficial for cardiovascular and cerebrovascular diseases
Epimedium leaching solution and non-amino acid fractions extracted from 200% Epimedium water extract tablets have a significant effect on the coronary flow of the ex vivo rabbit heart. 200% Epimedium Decoction 0.5ml is perfused to the heart of ex vivo guinea pigs, which can increase their coronary flow by an average of 126.6%. The non-amino acid portion extracted from Epimedium is given intravenously to dogs, which can significantly increase coronary flow and significantly reduce coronary resistance, but has no significant effect on the heart. After intravenous injection of 1g/kg of non-amino acid part in anesthetic rabbits, the effect of transient reduction of left diastolic blood pressure and can temporarily reduce the difference in left diastolic pressure, but this effect is weak. The non-amino acid part of Epimedium has a protective effect on acute myocardial ischemia in rats caused by posterior pituitary lobulin.

*Item*	*Standard*	*Test Method*
Assay	Icariin ≥10%	HPLC
Appearance	Brown Yellow Powder	Visual
Odor	Characteristic	Organoleptic
Particle Size	≥95% pass 80 mesh	Ch. P. C. Rule 47
Loss on Drying	≤5.00%	Ch. P. C. Rule 52
Ash	≤5.00%	Ch. P. C. Rule 2302
Heavy Metals	≤10mg/kg	Colorimetric method
Arsenic (As)	≤3mg/kg	Ch. P. C. Rule 21-ICP-MS
Lead (Pb)	≤2mg/kg	Ch. P. C. Rule 21-ICP-MS
Mercury (Hg)	≤2mg/kg	Ch. P. C. Rule 21-ICP-MS
Cadmium (Cd)	≤2mg/kg	Ch. P. C. Rule 21-ICP-MS
Ethanol	≤500mg/kg	GC-MS
Total Plate Count	≤5000CFU/g	ISO 4833-1:2013
Total Yeast & Mold	≤500CFU/g	ISO 21527:2008
Coliforms	≤10CFU/g	ISO 21527:2008
Salmonella	Negative	ISO 6579-1:2017

*Supplier's* *Name*	Hunan Delore Natural Products Co., Ltd
*Supplier'sEmail***	info@delore.cn
*Supplier'sWebsite***	www.delore.cn /www.deloresolutions.com
*Supplier's Address*	Bld#7B, Depu Parkview Green, Changsha, Hunan, 410100, China